Akt3-Mediated Protection Against Inflammatory Demyelinating Disease
نویسندگان
چکیده
منابع مشابه
Inflammatory demyelinating disease mimicking malignant glioma.
UNLABELLED The differential diagnosis between inflammatory demyelinating disease and malignant glioma is difficult based only on neuroimaging methods. METHODS Four patients with inflammatory demyelinating disease who presented with clinical and neuroimaging findings strongly suggestive of malignant glioma were examined. RESULTS MRI showed a mass lesion with prolonged T1 and T2 values and ga...
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Infection of dendritic and glial cells with Theiler's murine encephalomyelitis virus (TMEV) induces various cytokines via Toll-like receptor- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways. However, the involvement and role of MDA5 in cytokine gene activation and the pathogenesis of TMEV-induced demyelinating disease are largely unknown. In this study, we demonstrate t...
متن کاملChronic inflammatory demyelinating polyneuropathy.
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare neurological disease. Definitive therapy is not yet established. We report our use of intravenous Immunoglobulin (iv IgG) in two cases of CIDP and review the therapeutic options available. Intravenous IgG is a ubiquitous practical treatment particularly in patients who do not respond to steroids and where a rapid response is req...
متن کاملChronic Inflammatory Demyelinating Polyneuropathy
Touch MEdical MEdia 47 Diabetes mellitus (DM) is a leading cause of peripheral neuropathy.1–3 A distal symmetric sensorimotor polyneuropathy (DSP), is the most common manifestation,4 and is considered to be mainly due to axonal degeneration and progressive loss of nerve fibers.5–7 However, focal and multifocal peripheral nerve lesions, comprising cranial, thoracoabdominal, and limb nerve lesion...
متن کاملChronic inflammatory demyelinating polyneuropathy.
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated disease of the peripheral nervous system with a prevalence of 1-2/100,000. Clinical and experimental findings suggest a role of immune pathomechanisms;however, the target antigens are still unknown. Beside classic CIDP with symmetrical proximal and distal paresis, subgroups of CIDP with pure motor or sensory...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2019
ISSN: 1664-3224
DOI: 10.3389/fimmu.2019.01738